Arsenium
As
33
74.922
1s22s22p63s23p63d104s24p3
Biological significance

➤ It is localized in such body structures as brain cells, muscles, liver, lungs, and skin derivatives (hair, nails).

➤ It has a catalytic effect in the process of hemoglobin synthesis.

Excess in the body

➤ Leads to dermatologic diseases, respiratory diseases, heart muscle, central nervous system and reproductive system.


Nephropathy is a characteristic condition.


➤ Increased vascular wall permeability and hemocapillary plethora.


➤ Causes the formation of necrobiotic sites in the structures of vital organs: liver, heart, intestines, kidneys.


➤ Causes intoxication of the body with various types of pesticides and contaminated water.


➤ Causes carcinogenic effects on the respiratory system and skin.

Deficiency in the body

➤ Decreased resistance of the immune system to foreign factors, possible occurrence of skin diseases and disruption of hematopoiesis.

➤ A feeling of exhaustion accompanied by a deterioration in overall health.

Drugs/dose

​➤ As2O3 (Arsenic trioxide)

​➤ N2HAsO4 ·7H2 O (Sodium arsenate) - 1% solution (together with strychnine): general strengthening and tonic.

​➤ Al2O3 (arsenic anhydride, white arsenic) 0.005 g: the drug has a necrotizing effect for the treatment of diseases of dermatological origin and painful conditions of the body (anemia, neurasthenia).

Conventional medicine

➤ In the treatment of diseases of venereal origin (novarsenol, miarsenol).


➤ Widely used in dental practice for the devitalization of tooth pulp.

Unconventional medicine

​​➤ ​The arsenic compound salvarsan is historically the first effective and harmless etiotropic medicine against syphilis and psoriasis.

Toxic effect/antidote

➤ As2O3 - white arsenic, a strong poison.

➤ Arsine AsH3 - gas - the most poisonous arsenic compound (AsH3 0.005 g - instant death). Arsenic organic compounds affect the upper respiratory tract.

➤ Antidotes: Na2S2O3 , MgS2O3 , milk casein binds arsenic.

Interesting facts (CH3)3

➤ In the III-IV centuries BC, the metal arsenic was mentioned - the only metal with a boiling point below the melting point.


➤ Lewisite is a poisonous substance with a skin-bursting (blistering) effect.


➤ Aqua Tofana is a poison containing an aqueous solution of arsenic acid.


➤ Trimethylarsen(CH3)As - has a characteristic odor of garlic, and was used to poison Napoleon.

Chemist Albetrus Magnus
on how he discovered Arsenium


© All Rights Reserved.

Made on
Tilda