Astatine
At
85
210
1s22s22p63s23p63d104s24p64d104f14
5s25p65d106s26p5
Biological significance

➤ It can be used in medical practice to treat certain types of carcinomas.

➤ In the human body, it accumulates in the thyroid gland, spleen, lungs, and adrenal glands.

Excess in the body

➤ Cephalalgia, vertigo, general weakness of the body and hypofunction of visceral organs are observed.

Deficiency in the body

-

Drugs/dose

-

Conventional medicine

211At has been used in radiation therapy as a source of ionizing radiation for the treatment of thyroid tumors.

Unconventional medicine

➤ Artificial thyroid hormone is used in thyroid therapy.

Toxic effect/antidote

➤ A negative effect on the skin can lead to eczema, coxarthrosis, and thyroid cancer.

➤ SCN rhodanide ion blocks the accumulation of At in the thyroid gland.



➤ There is no specific antidote.

Interesting facts

➤ Austrian chemists B. Karlik and T. Bernert were the first to find At in nature in radon decay products.

➤ In 1953, the American radiochemists E. Hoyd and A. Giorso chemically isolated 219At from franc-223.

➤ But it is easier to produce At artificially by irradiating gold, bismuth, etc.

➤ The At properties were carried out with concentrations of 10-9 - 10-13 g/l.

Chemist Dale Corson
about how he discovered Astatine

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