Bismuth
Bi
83
208.98
1s22s22p63s23p63d104s24p64d104f14
5s25p65d106s26p3
Biological significance

➤ Provides protection of the gastric mucosa due to exposure to harmful substances.

➤ Supports normal functioning of the cardiovascular system.

➤ Contained in very small amounts in the body.

Excess in the body

➤ Leads to toxic reactions on the skin, causes the development of gastrointestinal disorders and uremia.

Deficiency in the body

➤ Gastrointestinal disorders, especially dysfunction of the gastric mucosa and development of ulcers.

➤ Decreased body performance and inhibition of immune activity may occur.

Drugs/dose

➤ C6HBiBr4O3 (Bibrocathol) - Ointment 20mg/g - for non-infectious eye inflammation, chronic blepharitis.

➤ C12H10BiK3O14 (Bismuth subcitrate colloidal) - Tablet. 120 mg - for gastric and duodenal ulcers

➤ C14H6BiO6 (Bismuth subhalate) - Soup. 0.04 mg - symptomatic treatment of haemorrhoids and fissures of the anus.

➤ Bismuth and its preparations have bactericidal, bacteriostatic, anti-inflammatory and adsorption effects

➤ Bi2O3 - for the preparation of antiseptic and healing products - dermatol xeroform, bismoverol, etc.

➤ (BiO)NO3 (Basic bismuth nitrate) - Vicalin contains 0.35 g of salt - for the treatment of stomach ulcers.

➤ Bi2O3 - as part of the powder "Bisphate" - a filling material in dentistry.

Conventional medicine

➤ The drug has anti-inflammatory effect on the gastrointestinal tract due to the formation of a protective layer on the walls.

➤ It is used in the treatment of gastroesophageal reflex and ragaditis.

➤ The antidiarrheal effect is due to the ability of Bi to bind H2S (intestinal motility stimulant) and forms a film of albuminates on the intestinal walls, reduces the sensitivity of nerve fibers, relieves pain and reflexively increases intestinal motility.



Unconventional medicine

➤ Bismuth sulfate is used to treat gastrointestinal disorders and heartburn.

Toxic effect/antidote

➤ Bi inhibits the action of some enzymes containing an NH2 group in their structure.

➤ After absorption into the body, Bi compounds begin to accumulate in the kidneys, liver, spleen, lung sacs, and brain tissue.

➤ It enters the body through the skin, respiratory tract, and digestive tract.

➤ Intoxication results in abdominal pain, pharyngeal reflex, vertigo, generalized body weakness, and manifestations of central nervous system damage, bismuth gingivitis, and stomatitis.



➤ Antidote: sodium dimercaptosuccinate (DMSN), unitiol.



Interesting facts

➤ Bi is both brittle and soft, has low thermal conductivity, and is diamagnetic (not attracted to the poles of a magnet).

➤ Solid Bi is characterised by covalent-metallic bonds, while molten Bi has only metallic bonds.

➤ Bi alloys with Cd, Sn, and Pb are used in fire extinguishers.

➤ Bi is used as a cooling agent in nuclear reactors.

➤ Bi salts are used to make pearlescent lipstick.

➤ Salt (BiO)NO3 - in the Renaissance, it was used in cosmetics called Spanish whitewash.

Chemist Claude Fortuyn
about how he discovered Bismuth

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