Fluorine
F
9
18.998
1s22s22p5
Biological significance

➤ Promotes the formation of hard tooth tissue and enamel, prevents tooth gaps, improves the condition of hair follicles, nails, supports immune activity, accelerates bone growth, prevents osteoporosis; hematopoiesis processes, circulates in the blood with albumin.

Excess in the body

➤ Disorders of carbohydrate and phosphate metabolism in the body can lead to changes in the structure of bone tissue and tooth enamel, impaired kidney function and metabolism. There is also a decrease in blood clotting, an increase in neuromuscular excitability and vascular permeability.

➤ Thyroiditis may occur due to displacement of iodine from thyroxine.

Deficiency in the body

➤ Leads to dental gap disease, nail desquamation, and bone structure disorders.

Drugs/dose

➤ NaF (sodium fluoride) - 1.1-2.2 mg tablets; 0.05% and 0.2% rinse solutions.

➤ Fluorothane C2HClBrF3 - 50 and 250 ml liquid for anesthesia.

➤ Organic compounds containing F, e.g: C21H23ClFNO2 - haloperidol - neuroleptic, antipsychotic and antiemetic.

Conventional medicine

➤ In the treatment and control of metastases of organs of the upper and lower body.

➤ Contained in toothpastes and rinses to protect against tooth decay.

➤ Some drugs for the prevention of osteoporosis contain fluoride compounds.

Unconventional medicine

➤ Consuming a diet enriched with seafood and walnuts containing fluoride helps to strengthen bone and tooth enamel.

Toxic effect/antidote

➤ Leads to dental fluorosis and osteopenia and vasodystonia; renal dysfunction and NS disorders.


➤ Antidote: 10% solution of calcium chloride.

Interesting facts

➤ Fluorine is the most electronegative, most active, most reactive, and most aggressive element.

➤ Freon CF4 is a refrigerant in refrigerators.

➤ 1 litre of seawater contains 0.3 mg of F, oyster shells contain 20 times more, and coral reefs contain millions of tonnes of fluoride.

Chemist Friedrich Heinrich Margant
on how he discovered fluoride


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