Manganese
Mn
25
54.938
1s22s22p63s23p63d54s2
Biological significance

➤ Part of the citrate cycle enzymes, forms collagen and transmits signal impulses between neurons.

➤ It is involved in thyroid metabolism.

➤ Helps to form healthy cartilage and bone structures.

➤ Manganese regulates the metabolism of fats and carbohydrates, which prevents the development of atheromatosis.

➤ Accelerates the formation of antibodies.

➤ Participates in the synthesis of vitamin C.

➤ It has a lipotropic effect - reduces the deposition of fats in the body.

➤ Participates in oxidative phosphorylation, is necessary for normal insulin secretion.

Excess in the body

➤ Causes mitochondrial dysfunction in cells, malfunction of the central nervous system,

impaired functioning of the reproductive system and gastrointestinal disorders.



Deficiency in the body

➤ Loss of the function of perception of the information provided, muscle cramps and spasms.

➤ Muscle and joint pain symptoms (myalgia and arthralgia).

➤ Motor and joint disorders with vulnerability to sprains and strains and arthritis.

➤ Progressive deterioration of visual acuity and thyroid dysfunction.

➤ The growth of derivative components of the skin, such as nails and hair, is slowed down.

➤ Excessive cholesterol levels lead to overweight.

Drugs/dose

➤ KMnO4 (potassium permanganate) - 0.01 - 0.1% solutions for gargling.

➤ 2-5% for moistening burns.

➤ 0.02-0.1% solutions for gastric lavage in case of poisoning.

Conventional medicine

➤ In medical diagnostics and manipulations, it is used to enhance the clarity of images during nuclear magnetic resonance imaging.

➤Manganese adds saturation and contrast to medical prostheses for better visualization in MRI images.

Unconventional medicine

➤ A trace element contained in walnuts and used to treat gastrointestinal inflammation, vitamin deficiency, exudative diathesis, bloody discharge, and gout.

➤ It is contained in blueberry leaves, the infusion of which is used to prevent the mild stages of diabetes, as well as in pyelonephritis, cystitis, urethritis, gastrocolitis and chronic enterocolitis.

Toxic effect/antidote

➤ MnO2 - affects the respiratory system, in particular, irritates lung tissue and causes dust disease.

➤ MnCl2 - irritates the skin, eyes and respiratory tract.

➤ It has cumulative properties; it affects nervous tissues and blood vessels.



➤ Antidote: vitamin B1, B6, ascorbic acid are used.

Interesting facts

➤ The pyrolysis of MnO2 * H₂O was known to Pliny the Elder in the 1st century AD.

➤ Concretions are mineral compounds of Mn found at the bottom of the Pacific Ocean - up to 1.5 billion tons.

➤ In plants, Mn accelerates the synthesis of chlorophyll and vitamin C.

➤ Intravenous infusion of MnSO4 is used to save people who have been bitten by a caracurta.

➤ The "mineral chameleon" - pyrrolusite fused with nitrate and KOH in aqueous solution - is green, then turns blue, purple, crimson, and turns green again when shaken.

Chemist Wilhelm Chalet
on how he discovered the Brazier


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