➤ The main depot of Ni in the body is the liver, kidneys, and pancreas.

➤ Stimulates hematopoiesis and hemoglobin formation.

➤ It is a part of the structure and functioning of hereditary material.

➤ It activates several enzymes, accelerates the metabolism of carbohydrates and fats, and helps regulate blood pressure.

➤ The daily allowance is 0.02-0.03 mg/kg.

➤ Overdose causes: tachycardia, anemia, dermatological diseases, decreased immunity, inflammation of the mucous membranes of the upper respiratory tract, pulmonary hypertrophy and brain edema, increased chances of carcinoma, gastrointestinal disorders, respiratory problems, cephalgia and irritation.

➤ Anemia, immunodeficiency, and dermatological diseases appear.

➤NiSO₄ -6H₂O, (Nickel sulphate) - Flac. 0.4865mg/ml.

➤ It is used as a therapeutic and prophylactic measure for iron deficiency anemia and stabilizes hemoglobin content in the human body.

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➤ Irritate the outer skin and cause inflammation of the mucous membranes and problems with the respiratory system.

➤ Cause serious lung diseases (bronchitis, pneumonia, asthma, lung cancer).

➤ Causes abdominal cramps, pharyngeal reflexes, and gastrointestinal disorders.

➤ Nickel powder enters the human body through the lungs.

➤ Antidote: deferoxamine.

➤ Monel-metal - Ni-Cu alloy (A. Monel is the president of the International Nickel Company) - high chemical resistance and mechanical properties.

➤ Neissilber, nichrome, melchior - alloys of Ni (20%) with Cu, Zn.

➤ Ni in organic chemistry - a catalyst in hydrogenation reactions.

➤ Carbonyl Ni - NiC₄O₄ is a liquid, volatile substance.

➤ Albino animals have an increased concentration of Ni in the blood.

➤ Ni dimethyl glyoxymate is a component of lipstick.