➤ Some platinum compounds have bactericidal, bacteriostatic and immunosuppressive effects when they enter the body.

➤ They are considered to be moderately active carcinogens.

➤ Cisplatin is an anticancer drug.

➤ Causes platinumosis, which is accompanied by allergic reactions, hearing loss, gastrointestinal disorders, and uremia.

➤ Rapid changes in concentration towards deficiency cause nephropathy and disruption of the carbohydrate metabolism cycle.

➤ [Pt(NH₃)₂Cl₂] (Cisplatin) 0.5mg/ml - for tumors of the cervix, lungs, stomach, bladder, etc.

➤ C₆H₁₂N₂O₄Pt (Carboplatin) 10mg/ml - breast, lung, sarcoma, myeloma cancer.

➤ C₆H₁₄N₂O₄Pt (Oxaliplatin) - drip: colon cancer.

➤ Pt-Ir, Pt-Au alloys are used in dentistry.

➤ It is used during chemotherapy of recurrent carcinoma.

➤ In the production of orthodontic structures in dental practice.

➤ Formation of surgical instruments that can be sterilized with an alcohol flame and do not show an oxidizing effect.

➤ Platinum is used in the production of needles for artificial pneumothorax.

➤ The vancomycin-iron-platinum complex identifies and simultaneously neutralizes gram-positive bacteria at ultra-low concentrations.

➤ Cisplatin as an antiproliferative drug is characterized by kidney toxicity.

➤ In the form of ototoxicity, it causes hearing impairment.

➤ In its potentially neurotoxic form, it causes peripheral neuropathy.

➤ Antidote: Symptomatic therapy.

➤ Until the seventeenth century, this precious metal was thrown away with waste rock.

➤ Pt can form complexes in which all six ligands are different.

➤ Pt is widely used to make laboratory glassware.

➤ Pt acts as a catalyst.

➤ The 1 kg reference is a cylinder with a diameter of 39 mm and a height of 39 mm.

➤ The largest Pt nuggets are 5918.4 g and 7860.5 g.