Uranium
U
92
238.03
1s22s22p63s23p63d104s24p64d104f14
5s25p65d105f36s26p66d17s2
Biological significance

➤ Localized in the endocrine organs: adrenal glands, pancreas, thymus, pineal gland, kidneys, and bone tissue.

➤ The total uranium content in the human body is 2.0 × 10-6 g.

➤ Higher concentrations have radiation toxic effects on the body due to uranium decay products.

Excess in the body

➤ Radiation causes cell necrosis in the body.

Deficiency in the body

-

Drugs/dose

➤ Uranium acetate (C3 HCOO)3U - used to treat neurolysis.

Conventional medicine

➤ During diagnostic examinations, to establish a treatment plan for carcinomas by inhibiting their metabolism.

Unconventional medicine

➤ Uranium compounds are used to make special protective clothing, which have a protective effect against the penetration of radiation rays.

➤ In surgical practice, it is used in the form of sterilization materials for surgical equipment.

➤ It is of great importance during chemotherapy.

Toxic effect/antidote

➤ Administration of 2 mg/kg body weight causes coma.


➤ Antidote: chelating agents - Trilon B.

Interesting facts

➤ Natural uranium isotopes give off two types of radiation: alpha particles (Ne nuclei) and spontaneous fission, which leads to a chain reaction.

➤ The uranium-lead method determines the time of mineral formation, and the age of meteorites has been used to determine the age of the planet Earth.

Chemist Martin Heinrich Klaproth
about how he discovered Uranium

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