Zinc
Zn
30
65.380
1s22s22p63s23p63d104s2
Biological significance

➤ In the human body, Zinc is present in the retina, liver, and is also part of muscles (60%).

➤ It is involved in nucleoprotein metabolism and fat metabolism.

➤ D. Hodgkin discovered that Zinc is a component of insulin and received the 1964 Nobel Prize for this.

➤ Carbonic anhydrase catalyzes the reverse conversion of carbonic acid (H2CO3↔CO2+H2O).

➤ Alcohol dehydrogenase in the human body contains Zn molecules and is able to promote the combustion of ethanol into aldehyde.

➤ Zn is a part of the enzyme revertase and initiates the division of cancer cells.

Excess in the body

➤ Excessive amounts of Zinc cause dermatoses with non-healing skin ulcers and alopecia.

➤ There is also a decrease in immunity, which subsequently leads to the development of rheumatoid arthritis.

➤ Causes disorganization of the central nervous system, dysgeusia and dysosmia develop, and a melancholic and apathetic state of a person is present.

➤ Excessive Zn is not accumulated but excreted.

Deficiency in the body

➤ It has an effect on the immune system, which reduces its function.

➤ It causes dysfunction of gonadal production, which leads to impaired primary and secondary sexual characteristics.

➤ Loss of appetite and dysgeusia are observed. Impaired skeletal development and decreased ATP synthesis.

➤ Promotes increased fragility and brittleness of skin derivatives (hair and nails).

Drugs/dose

➤ ZnSO4+H2O (Zinc Sulfate) - 0.2% solution -: astringent, anti-inflammatory effect.

➤ ZnCl2 (Zinc Chloride) aqueous eye injections: astringent, cauterizing effect.

➤ ZnO - in the composition of impression material used in orthopedics; in the composition of filling materials; used in the form of powders, ointments.

Conventional medicine

➤ It has antibacterial and astringent effects.

➤ Boosts the immune system.

Unconventional medicine

➤ Zinc adjuvants are effective in dermatoses, as well as in severe forms of acne and cystic acne.

Toxic effect/antidote

➤ Causes asthenia of the whole body, cephalgia and asphyxia.

➤ Disrupts the gastrointestinal tract, namely the pharyngeal reflex.

➤ Adversely affects kidney and liver function.

➤ In high concentrations, Zn compounds exhibit toxic properties.


➤ Trilon B is an effective antidote and also has cleansing properties.

Interesting facts

➤ Zinc was mined in India in the 5th century BC.

➤ The alloy of Zinc and Copper is called brass.

➤ At 99.9-99.99% purity, Zn is soluble in acids, 99.999% is insoluble.

➤ 40% of the world's Zn production is used to improve the corrosion resistance of steel. Zinc whitewashes are called Zn oxide according to the chemical nomenclature.

➤ High concentrations of Zn are present in snake venom, particularly cobra venom.

➤ "Chipmunk" ore is a mixture of ZnS and feldspar.

Chemist William Champion
on how he discovered Zinc


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